The molecular complexes of the monoammonium salt of glycyrrhizic acid with urea, thiourea, methylolthiourea and their fungicidal activity

AbstractThis article reports on the preparation of inclusion compounds of the monoammonium salt of glycyrrhizic acid with urea, thiourea and methylolthiourea. Based on the spectral data, it was concluded that complexation occurs due to the interaction of polar groups of the components. The composition of the complexes was studied using the isomolar series method. Equilibrium constants and the change in the Gibbs free energy of the complexation process were also calculated. The biological activity of complex compounds has been studied using the example of fungicidal activity against some of the most common pathogenic fungi Fusarium. The obtained compounds can be used as stimulants in agriculture.

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