Synthesis and biological activity

351 ta ish

Design, combinatorial synthesis and cytotoxic activity of 2-substituted furo[2,3-d]pyrimidinone and pyrrolo[2,3-d]pyrimidinone library
Buer Song, Lifei Nie, Khurshed Bozorov +3
MaqolaSynthesis and Biological EvaluationMolecular Diversity202221 iqtibos
ABI
Synthesis of Substituted Thieno[2,3‐d]pyrimidin‐4‐ones and Their Testing for Evaluation of Cytotoxic Activity on Mammalian Cell Models
Khurshed Bozorov, Nilufar Z. Mamadalieva, Burkhon Elmuradov +5
MaqolaOchiq kirishSynthesis of heterocyclic compoundsJournal of Chemistry201218 iqtibos
ABI
Design, synthesis, in vitro evaluation of a new pyrrolo[1,2‐a]thiazolo[5,4‐d]pyrimidinone derivatives as cholinesterase inhibitors against Alzheimer's disease
Yan Zeng, Lifei Nie, Liu Liu +6
MaqolaCholinesterase and Neurodegenerative DiseasesJournal of Heterocyclic Chemistry202218 iqtibos
ABI
Recent developments regarding the use of thieno[2,3-d]pyrimidin-4-one derivatives in medicinal chemistry, with a focus on their synthesis and anticancer properties
Khurshed Bozorov, Jiang-Yu Zhao, Burkhon Elmuradov +2
Sharh maqolaQuinazolinone synthesis and applicationsEuropean Journal of Medicinal Chemistry201516 iqtibos
ABI
<scp>2‐substituted</scp> tricyclic oxazolo[5,4‐d]pyrimidine library: Design, synthesis, and cytotoxicity activity
Yan Zeng, Lifei Nie, Khurshed Bozorov +4
MaqolaQuinazolinone synthesis and applicationsJournal of Heterocyclic Chemistry202112 iqtibos
ABI
Discovery of diethyl 2,5-diaminothiophene-3,4-dicarboxylate derivatives as potent anticancer and antimicrobial agents and screening of anti-diabetic activity: Synthesis and in vitro biological evaluation. Part 1
Khurshed Bozorov, Hairong Ma, Jiangyu Zhao +7
MaqolaSynthesis and biological activityEuropean Journal of Medicinal Chemistry201411 iqtibos
ABI
A Convenient One-pot Synthesis of 2,3-Disubstituted Thieno[2,3-d]pyrimidin-4(3H)-ones from 2H-Thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, Aromatic Aldehydes and Amines
Feize Liu, Xueling Hou, Li Fei Nie +3
MaqolaOchiq kirishQuinazolinone synthesis and applicationsSynOpen201811 iqtibos
ABI
Synthesis and anticancer activity of ethyl 5‐amino‐1‐N‐substituted‐imidazole‐4‐carboxylate building blocks
Zukela Ruzi, Lifei Nie, Khurshed Bozorov +2
MaqolaSynthesis and Characterization of Heterocyclic CompoundsArchiv der Pharmazie202111 iqtibos
ABI
Evaluation of the Local Anesthetic Activity, Acute Toxicity, and Structure–Toxicity Relationship in Series of Synthesized 1-Aryltetrahydroisoquinoline Alkaloid Derivatives In Vivo and In Silico
Azizbek Azamatov, Sherzod Zhurakulov, Валентина И. Виноградова +6
MaqolaOchiq kirishSynthesis and Biological ActivityMolecules202310 iqtibos
ABI
Synthesis and in vitro biological evaluation of novel diaminothiophene scaffolds as antitumor and anti-influenza virus agents. Part 2
Khurshed Bozorov, Jiang Zhao, Li Fei Nie +7
MaqolaOchiq kirishClick Chemistry and ApplicationsRSC Advances201710 iqtibos
ABI
Coumarins and bicoumarin from Ferula sumbul: anti-HIV activity and inhibition of cytokine release
Ping Zhou, Yoshihisa Takaishi, Hong‐Quan Duan +6
MaqolaPlant chemical constituents analysisPhytochemistry200010 iqtibos
ABI
Synthesis of tricyclic pyrazolopyrimidine arylidene ester derivatives and their cytotoxic and molecular docking evaluations
Tong Lu, Lifei Nie, Danling Tang +3
MaqolaSynthesis and biological activityJournal of Heterocyclic Chemistry202410 iqtibos
ABI
Novel pyrazolo[3,4-d]pyrimidines as potential anticancer agents: Synthesis, VEGFR-2 inhibition, and mechanisms of action
Zukela Ruzi, Khurshed Bozorov, Lifei Nie +2
MaqolaOchiq kirishSynthesis and biological activityBiomedicine & Pharmacotherapy20229 iqtibos
ABI
Chemical transformations of mackinazolinone and its derivatives
Azizbek Nasrullaev, Ж. Э. Турдибаев, Burkhon Elmuradov +3
MaqolaQuinazolinone synthesis and applicationsChemistry of Natural Compounds20128 iqtibos
ABI
Reaction of 2,3-tetramethylen-3,4-dihydroquinazol-4-one and its derivatives with aromatic aldehydes and furfurol
А. Ш. Абдуразаков, Burkhon Elmuradov, Ж. Э. Турдибаев +1
MaqolaQuinazolinone synthesis and applicationsChemistry of Natural Compounds20098 iqtibos
ABI
Analgesic and Anti-Inflammatory Effects of 1-(4'-Dimethylaminophenyl)-6, 7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline Hydrochloride
Khilola A. Rakhmanova, Sherzod Zhurakulov, Firuza M. Tursunkhodjayeva +2
MaqolaOchiq kirishChemical synthesis and pharmacological studiesBiomedical & Pharmacology Journal20228 iqtibos
ABI
1,2,3-Triazole-containing hybrids as leads in medicinal chemistry: A recent overview
Khurshed Bozorov, Jiangyu Zhao, Haji Akber Aisa
Sharh maqolaOchiq kirishClick Chemistry and ApplicationsBioorganic & Medicinal Chemistry20197 iqtibos
ABI
Synthesis of 6-benzylaminopurine and the study of biological active properties of cotton C-6424 plants
Gulbakhar Baymuratova, Khasan Nasimov, Foziljon Saitkulov
MaqolaOchiq kirishSynthesis and biological activityE3S Web of Conferences20237 iqtibos
ABI
Synthesis of Novel 7-Phenyl-2,3-Dihydropyrrolo[2,1-b]Quinazolin-9(1H)-ones as Cholinesterase Inhibitors Targeting Alzheimer’s Disease Through Suzuki–Miyaura Cross-Coupling Reaction
Davron Turgunov, Lifei Nie, Azizbek Nasrullaev +7
MaqolaOchiq kirishCholinesterase and Neurodegenerative DiseasesMolecules20257 iqtibos
ABI
Synthesis, bioinformatics and biological evaluation of novel pyridine based on 8-hydroxyquinoline derivatives as antibacterial agents: DFT, molecular docking and ADME/T studies
Mohamed Rbaa, Asmaa Oubihi, Halima Hajji +7
MaqolaSynthesis and biological activityJournal of Molecular Structure20217 iqtibos
ABI
2,2′-Bis{8-[(benzylamino)methylidene]-1,6-dihydroxy-5-isopropyl-3-methylnaphthalen-7(8H)-one}
Shukhrat M. Hakberdiev, Samat A. Talipov, D. N. Dalimov +1
MaqolaOchiq kirishCrystal structures of chemical compoundsActa Crystallographica Section E Structure Reports Online20136 iqtibos
ABI
Effect and Spectroscopic Analysis of Solutions in Trychloratsetylpyrogallol Synthesis
Ruzimurod Sattorovich Jurayev, Azimjon Uralovich Choriev, Navruz Toyirovich Qaxxorov
MaqolaOchiq kirishInorganic and Organometallic Chemistry20236 iqtibos
ABI
2-Aminothiophene scaffolds: Diverse biological and pharmacological attributes in medicinal chemistry
Khurshed Bozorov, Li Fei Nie, Jiangyu Zhao +1
Sharh maqolaSynthesis and biological activityEuropean Journal of Medicinal Chemistry20176 iqtibos
ABI
2-Methyl-4-oxo-6,7,8,9-tetrahydrothieno[2′,3′:4,5]pyrimidino[1,2-a]pyridine-3-carboxylic acid
Burkhon Elmuradov, Khurshed Bozorov, R. Ya. Okmanov +2
MaqolaOchiq kirishCrystal structures of chemical compoundsActa Crystallographica Section E Structure Reports Online20116 iqtibos
ABI
Discovery of novel (E)-1-methyl-9-(3-methylbenzylidene)-6,7,8,9-tetrahydropyrazolo[3,4-d]pyrido[1,2-a]pyrimidin-4(1H)-one as DDR2 kinase inhibitor: Synthesis, molecular docking, and anticancer properties
Zukela Ruzi, Khurshed Bozorov, Lifei Nie +2
MaqolaOchiq kirishSynthesis and biological activityBioorganic Chemistry20236 iqtibos
ABI

Synthesis and biological activity

Design, combinatorial synthesis and cytotoxic activity of 2-substituted furo[2,3-d]pyrimidinone and pyrrolo[2,3-d]pyrimidinone library

Synthesis of Substituted Thieno[2,3‐<i>d</i>]pyrimidin‐4‐ones and Their Testing for Evaluation of Cytotoxic Activity on Mammalian Cell Models

Design, synthesis, in vitro evaluation of a new pyrrolo[1,2‐<i>a</i>]thiazolo[5,4‐<i>d</i>]pyrimidinone derivatives as cholinesterase inhibitors against Alzheimer's disease

Recent developments regarding the use of thieno[2,3-d]pyrimidin-4-one derivatives in medicinal chemistry, with a focus on their synthesis and anticancer properties

<scp>2‐substituted</scp> tricyclic oxazolo[5,4‐<i>d</i>]pyrimidine library: Design, synthesis, and cytotoxicity activity

Discovery of diethyl 2,5-diaminothiophene-3,4-dicarboxylate derivatives as potent anticancer and antimicrobial agents and screening of anti-diabetic activity: Synthesis and in vitro biological evaluation. Part 1

A Convenient One-pot Synthesis of 2,3-Disubstituted Thieno[2,3-d]pyrimidin-4(3H)-ones from 2H-Thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, Aromatic Aldehydes and Amines

Synthesis and anticancer activity of ethyl 5‐amino‐1‐<i>N</i>‐substituted‐imidazole‐4‐carboxylate building blocks

Evaluation of the Local Anesthetic Activity, Acute Toxicity, and Structure–Toxicity Relationship in Series of Synthesized 1-Aryltetrahydroisoquinoline Alkaloid Derivatives In Vivo and In Silico

Synthesis and in vitro biological evaluation of novel diaminothiophene scaffolds as antitumor and anti-influenza virus agents. Part 2

Coumarins and bicoumarin from Ferula sumbul: anti-HIV activity and inhibition of cytokine release

Synthesis of tricyclic pyrazolopyrimidine arylidene ester derivatives and their cytotoxic and molecular docking evaluations

Novel pyrazolo[3,4-d]pyrimidines as potential anticancer agents: Synthesis, VEGFR-2 inhibition, and mechanisms of action

Chemical transformations of mackinazolinone and its derivatives

Reaction of 2,3-tetramethylen-3,4-dihydroquinazol-4-one and its derivatives with aromatic aldehydes and furfurol

Analgesic and Anti-Inflammatory Effects of 1-(4'-Dimethylaminophenyl)-6, 7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline Hydrochloride

1,2,3-Triazole-containing hybrids as leads in medicinal chemistry: A recent overview

Synthesis of 6-benzylaminopurine and the study of biological active properties of cotton C-6424 plants

Synthesis of Novel 7-Phenyl-2,3-Dihydropyrrolo[2,1-b]Quinazolin-9(1H)-ones as Cholinesterase Inhibitors Targeting Alzheimer’s Disease Through Suzuki–Miyaura Cross-Coupling Reaction

Synthesis, bioinformatics and biological evaluation of novel pyridine based on 8-hydroxyquinoline derivatives as antibacterial agents: DFT, molecular docking and ADME/T studies

2,2′-Bis{8-[(benzylamino)methylidene]-1,6-dihydroxy-5-isopropyl-3-methylnaphthalen-7(8<i>H</i>)-one}

Effect and Spectroscopic Analysis of Solutions in Trychloratsetylpyrogallol Synthesis

2-Aminothiophene scaffolds: Diverse biological and pharmacological attributes in medicinal chemistry

2-Methyl-4-oxo-6,7,8,9-tetrahydrothieno[2′,3′:4,5]pyrimidino[1,2-<i>a</i>]pyridine-3-carboxylic acid

Discovery of novel (E)-1-methyl-9-(3-methylbenzylidene)-6,7,8,9-tetrahydropyrazolo[3,4-d]pyrido[1,2-a]pyrimidin-4(1H)-one as DDR2 kinase inhibitor: Synthesis, molecular docking, and anticancer properties