The role of membrane structure in the activation of mitochondrial phospholipases. 1. Activation of mitochondrial phospholipases by lipid peroxidation products.
Timusheva YtTashkent State University, Biological Faculty, Department of Biophysics, Republic of UzbekistanOlga A. MareninovaVagina OnZamaraeva MvSalakhutdinov BaAripov TFTashmukhamedov Ba
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Annotatsiya
Induction of lipid peroxidation is shown to alter the structure of mitochondrial membrane and to activate endogenous phospholipases A2, C, D, and lysophospholipase A. Fe(2+)-, cumene hydroperoxide- and ultraviolet-induced lipid peroxidation results in the activation of mitochondrial phospholipases.
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