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Screening some of plants from Silene Genus for 20-Hydroxyecdysone

Nazim MamedovMedicinal Plant Program, University of Massachusetts, Amherst, MA 01003, USANilufar Z. MamadalievaLaboratory of Chemistry of Glycosides, Institute of the Chemistry of Plant Substances AS RUz, Tashkent 100170, UzbekistanAbdulaziz A. JanibekovLaboratory of Chemistry of Glycosides, Institute of the Chemistry of Plant Substances AS RUz, Tashkent 100170, UzbekistanLyle E. CrakerMedicinal Plant Program, University of Massachusetts, Amherst, MA 01003, USA
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Eight Silene species include S. brachuica , S. guntensis, S. linicola , S. oreina, S. praemixta , S. pseudotites, S. viridiflora and S. wallichiana were screened for the main ecdysteroid 20-hydroxyecdysone by HPLC using the UV spectroscopy. HPLC analyses have shown all Silene plants except S. oreina contain 20-hydroxyecdysone, but in different concentration. Studies have shown that S. praemixta and S. viridiflora are rich phytoecdysteroids containing plants and the yields of total ecdysteroids are 2.0% and 1.6%, respectively. The results of investigation species of Silene : S. brachuica, S. praemixta, S. viridiflora, S. guntensis, S. linicola, S. pseudotites and S. wallichiana showed that the yields of 20E of these plants are 0.03, 0.27, 0.35, 0.082, 0.367, 0.071 and 0.08% respectively. The plants of S. linicola, S. praemixta and S. viridiflora suggested to be used for production of ecdysteroids containing preparations.

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