Flavone glucosides from <i>Artemisia juncea</i>
B. S. OkhundedaevInstitute of the Chemistry of Plant Substances of the Academy Sciences of Uzbekistan, Tashkent, Uzbekistan;Markus BacherDivision of Chemistry of Renewables, Department of Chemistry, University of Natural Resources and Life Sciences, Vienna (BOKU University), Tulln, Austria;R. F. MukhamatkhanovaInstitute of the Chemistry of Plant Substances of the Academy Sciences of Uzbekistan, Tashkent, Uzbekistan;Ildar J. ShamyanovInstitute of the Chemistry of Plant Substances of the Academy Sciences of Uzbekistan, Tashkent, Uzbekistan;Gokhan ZenginDepartment of Biology, Faculty of Science, University of Selcuk, Konya, TurkeyStefan BöhmdorferDivision of Chemistry of Renewables, Department of Chemistry, University of Natural Resources and Life Sciences, Vienna (BOKU University), Tulln, Austria;Nilufar Z. MamadalievaInstitute of the Chemistry of Plant Substances of the Academy Sciences of Uzbekistan, Tashkent, Uzbekistan;Thomas RosenauDivision of Chemistry of Renewables, Department of Chemistry, University of Natural Resources and Life Sciences, Vienna (BOKU University), Tulln, Austria;
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Annotatsiya
A new flavone glucoside, 4′,5-dihydroxy-3′,5′,6-trimethoxyflavone-7-O-β-D-glucoside was obtained from aerial parts of Artemisia juncea, together with the known flavone eupatilin (5,7-dihydroxy-3′,4′,6-trimethoxyflavone). The compounds were comprehensively analytically characterized by IR, UV, NMR and HR-MS, and their chemical structures ascertained. The EtOAc fraction of A. juncea showed the strongest DPPH radical scavenging ability as well as reducing power (in CUPRAC and FRAP assays) and phosphomolybdenum activity. This fraction also exhibited the strongest inhibitory effects on tyrosinase. Additionally, the best antidiabetic effects were observed for eupatilin and the CHCl3 fraction.
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