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Anti-Ulcer Activity of<i>Adhatoda vasica</i>Nees

Neeta ShrivastavaDepartment of Pharmacognosy and Phytochemistry, B. V. Patel Pharmaceutical Education & Research Development Centre, Ahmedabad, Gujarat, IndiaAnshu SrivastavaDepartment of Pharmacognosy and Phytochemistry, B. V. Patel Pharmaceutical Education & Research Development Centre, Ahmedabad, Gujarat, IndiaAryamitra BanerjeeDepartment of Pharmacology and Toxicology, B. V. Patel Pharmaceutical Education & Research Development Centre, Ahmedabad, Gujarat, IndiaManish NivsarkarDepartment of Pharmacology and Toxicology, B. V. Patel Pharmaceutical Education & Research Development Centre, Ahmedabad, Gujarat, India
2006en
ABI

Annotatsiya

Adhatoda vasica Nees (Acantheceae), commonly known as Vasaka, is a well-known plant in indigenous systems of medicine and is used for its beneficial effects, particularly in bronchitis. The present investigation was carried out to study the antiulcer activity of Adhatoda vasica leaves using two ulcer models (1) Ethanol-induced, and (2) Pylorus ligation plus aspirin-induced models. Adhatoda vasica leaf powder showeda considerable degree of antiulcer activity in experimental rats when compared with a control. The highest degree of activity (80%) was observed in the ethanol-induced ulceration model. Results of the study suggest that in addition to its classically established pharmacological activities, the plant also has immense potential as an antiulcer agent of great therapeutic relevance.

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