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Chemical composition, antimicrobial and antioxidant activities of the essential oils of three Uzbek Lamiaceae species

Nilufar Z. MamadalievaInstitute of the Chemistry of Plant Substances of the Academy Sciences of Uzbekistan, Tashkent, UzbekistanFadia S. YoussefFaculty of Pharmacy, Department of Pharmacognosy, Ain Shams University, Cairo, EgyptMohamed L. AshourFaculty of Pharmacy, Department of Pharmacognosy, Ain Shams University, Cairo, EgyptС. А. СасмаковInstitute of the Chemistry of Plant Substances of the Academy Sciences of Uzbekistan, Tashkent, UzbekistanAntonio TiezziDepartment for the Innovation in Biological, Agro-food and Forestal Systems, Tuscia University, Viterbo, ItalyShakhnoza S. AzimovaInstitute of the Chemistry of Plant Substances of the Academy Sciences of Uzbekistan, Tashkent, Uzbekistan
Natural Product Researchjournal2018en
ABI

Annotatsiya

The chemical composition of the essential oil from the aerial parts of three Lamiaceae species from Uzbekistan was investigated by GC-MS analysis. β-Linalool (26.6%), α-terpineol (10.0%), coumarin (8.9%) and 4,5,7,7α-tetrahydro-4,4,7α-trimethyl-2(6H)-benzofuranone (5.4%) resulted as the main components of Ajuga turkestanica essential oil, while camphene (17.1%), 1,8-cineole (15.9%), β-cymene (7.9%) and limonene (7.4%) in Phlomis regelii. The essential oil of Thymus seravschanicus was dominated by thymol (37.5%), phellandral (26.0%), τ-terpinene (6.6%) and β-cymene (5.2%). The essential oils had considerable antimicrobial activity against different bacterial strains and fungi. Among the tested samples of essential oils, P. regelii essential oil has the significant antioxidant activity with IC50 value of 117.8 ± 8.02 μg/mL.

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