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A Convenient One-pot Synthesis of 2,3-Disubstituted Thieno[2,3-d]pyrimidin-4(3H)-ones from 2H-Thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, Aromatic Aldehydes and Amines

Feize LiuKey Laboratory of Plant Resources and Chemistry of Arid Zone, Xinjiang Technical Institute of Physics and ChemistryXueling HouKey Laboratory of Plant Resources and Chemistry of Arid Zone, Xinjiang Technical Institute of Physics and ChemistryLi Fei NieKey Laboratory of Plant Resources and Chemistry of Arid Zone, Xinjiang Technical Institute of Physics and ChemistryKhurshed BozorovInstitute of the Chemistry of Plant Substances, Academy of Sciences of UzbekistanMichael DeckerPharmazeutische und Medizinische Chemie, Institut für Pharmazie und LebensmittelchemieGuozheng HuangKey Laboratory of Plant Resources and Chemistry of Arid Zone, Xinjiang Technical Institute of Physics and Chemistry
SynOpenjournal2018en
ABI

Annotatsiya

An efficient, simple protocol has been established for convenient synthesis of novel 2,3-disubstituted thieno[2,3-d]pyrimidin-4(3H)-one derivatives in good to high yields through a one-pot, two-step and three-component reaction from 2H-thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, aromatic aldehydes, and amines.

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