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Diversity-oriented synthesis of amide derivatives of tricyclic thieno[2,3- d ]pyrimidin-4(3 H )-ones and evaluation of their influence on melanin synthesis in murine B16 cells
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Novel pyrazolo[3,4-d]pyrimidines as potential anticancer agents: Synthesis, VEGFR-2 inhibition, and mechanisms of action
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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1
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Inhibition of Leukocyte Functions by the Alkaloid Isaindigotone fromIsatis indigoticaand Some New Synthetic Derivatives
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Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors
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Design, Synthesis, and Evaluation of Isaindigotone Derivatives To Downregulate c-myc Transcription via Disrupting the Interaction of NM23-H2 with G-Quadruplex
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Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy
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Design, synthesis, and cytotoxic activities of isaindigotone derivatives as potential anti-gastric cancer agents
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A Novel Isaindigotone Derivative Displays Better Anti-Proliferation Activities and Induces Apoptosis in Gastric Cancer Cells
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Richard D. Taylor, Malcolm MacCoss, Alastair D. G. Lawson
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Ushbu ish iqtibos qilgan ishlar

Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

Design, combinatorial synthesis and cytotoxic activity of 2-substituted furo[2,3-d]pyrimidinone and pyrrolo[2,3-d]pyrimidinone library

Design, synthesis, in vitro evaluation of a new pyrrolo[1,2‐<i>a</i>]thiazolo[5,4‐<i>d</i>]pyrimidinone derivatives as cholinesterase inhibitors against Alzheimer's disease

Parallel synthesis of condensed pyrimidine-thiones and their antitumor activities

Diversity-oriented synthesis of amide derivatives of tricyclic thieno[2,3- <i>d</i> ]pyrimidin-4(3 <i>H</i> )-ones and evaluation of their influence on melanin synthesis in murine B16 cells

Recent developments regarding the use of thieno[2,3-d]pyrimidin-4-one derivatives in medicinal chemistry, with a focus on their synthesis and anticancer properties

Synthesis and biological evaluation of novel sulfonamide derivatives of tricyclic thieno[2,3-d]pyrimidin-4(3H)-ones on melanin synthesis in murine B16 cells

<scp>2‐substituted</scp> tricyclic oxazolo[5,4‐<i>d</i>]pyrimidine library: Design, synthesis, and cytotoxicity activity

Novel pyrazolo[3,4-d]pyrimidines as potential anticancer agents: Synthesis, VEGFR-2 inhibition, and mechanisms of action

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1

ADMETlab 2.0: an integrated online platform for accurate and comprehensive predictions of ADMET properties

Inhibition of Leukocyte Functions by the Alkaloid Isaindigotone from<i>Isatis indigotica</i>and Some New Synthetic Derivatives

Medicinal attributes of pyrazolo[3,4-d]pyrimidines: A review

Discovery of <i>N</i>-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1<i>H</i>-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors

Design, Synthesis, and Evaluation of Isaindigotone Derivatives To Downregulate <i>c-myc</i> Transcription via Disrupting the Interaction of NM23-H2 with G-Quadruplex

Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy

Design, synthesis, and cytotoxic activities of isaindigotone derivatives as potential anti-gastric cancer agents

A Novel Isaindigotone Derivative Displays Better Anti-Proliferation Activities and Induces Apoptosis in Gastric Cancer Cells

Rings in Drugs

SwissParam: A fast force field generation tool for small organic molecules

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