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Fabrication of an economical and environmentally friendly electrode utilizing fullerene modified with L-proline and coated with copper nanoparticles for enantioselective electro-organic henry reaction in the presence of NaCl electrolyte

Majid S. JabirDepartment of applied sciences/ university of technology, IraqHasan Sh. MajdiAli BasemFaculty of Engineering, Warith Al-Anbiyaa University, Karbala 56001, IraqMohamad J. AlfakerAmeer H. Al‐RubayeElyor BerdimurodovChemical & Materials Engineering, New Uzbekistan University, Movarounnahr street 1, Tashkent 100000, UzbekistanUsmonova Lola MallaevnaNavoi State Pedagogical Institute, Republic of UzbekistanHazem A. GhabbourDepartment of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura, Mansoura 35516, EgyptAbdulrahman A. AlmehiziaDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia
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This study focuses on the fabrication of an economical and environmentally friendly electrode for chiral electro-organic synthesis of (S)-2-Nitro-1-Phenylethanol derivatives 4(a-m) in good to excellent yields (90–96 %). The electrode is constructed using Fullerene modified with l-Proline and coated with copper nanoparticles (ox-Fullerene-Pro@Cu). The designed electrode aims to facilitate the synthesis of (S)-2-Nitro-1-Phenylethanol 4(a-m) derivatives efficiently. The utilization of sodium chloride as an electrolyte further enhances the electrochemical reaction. Following the electrode synthesis, comprehensive characterization and identification were conducted utilizing SEM, EDS, TEM, XPS, XRD, TGA, BET, CV and FT-IR analyses. The electrode's cost-effectiveness and eco-friendly nature make it a promising candidate for sustainable electro-organic synthesis processes. The synthesized (S)-2-Nitro-1-Phenylethanol derivatives 4(a-m) derivatives were identified and their properties reported through melting point, 1HNMR, Mass and CHN analyses.

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