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Biogenic Synthesis, Antimicrobial, Cytotoxic, and Photocatalytic Properties of Silver Nanoparticles Derived from <i>Lycium Depressum</i> Fruit Extract

İbrahi̇m ErolFaculty of Chemistry Department of Organic and Bioorganic Chemistry Samarkand State University University Blvd‐15 Samarkand UzbekistanÖmer HazmanFaculty of Chemistry Department of Organic and Bioorganic Chemistry Samarkand State University University Blvd‐15 Samarkand UzbekistanGofur KhamidovFaculty of Chemistry Department of Organic and Bioorganic Chemistry Samarkand State University University Blvd‐15 Samarkand UzbekistanNodira NurullayevaSamarkand State University Samarkand 140163 UzbekistanAlisher YusupovFaculty of Chemistry Department of Organic and Bioorganic Chemistry Samarkand State University University Blvd‐15 Samarkand UzbekistanDavlat TukhtaevFaculty of Chemistry Department of Organic and Bioorganic Chemistry Samarkand State University University Blvd‐15 Samarkand UzbekistanSanjar TillayevFaculty of Chemistry Department of Organic and Bioorganic Chemistry Samarkand State University University Blvd‐15 Samarkand UzbekistanMustafa Abdullah YılmazScience and Technology Research and Application Center Dicle University Diyarbakır 21280 Turkiye

ChemistrySelectjournal2025en

ABI

Annotatsiya

Abstract This study explores the biogenic synthesis of silver nanoparticles (LD‐AgNPs) using an aqueous extract (LDE) derived from Lycium depressum fruits and assesses their physicochemical and biological characteristics. The presence of phytochemicals in LDE, essential for nanoparticle formation and stabilization, was confirmed through LC–MS/MS analysis. UV–vis spectroscopy identified a surface plasmon resonance peak at 411 nm, and XRD analysis confirmed a face‐centered cubic crystal structure. TEM and SEM imaging determined an approximate nanoparticle size of 29 nm. Antimicrobial assessments revealed significant activity against Staphylococcus aureus and Escherichia coli , demonstrating efficacy comparable to commercial antibiotics. Cytotoxicity evaluations showed LD‐AgNPs exerted inhibitory effects on A549 lung cancer cells at 25 µg/mL, while toxicity in normal fibroblast cells (L929) was observed at 50 µg/mL. Additionally, LD‐AgNPs exhibited photocatalytic efficiency, degrading 74% of methylene blue. These findings suggest LD‐AgNPs are potential biomaterials for antimicrobial, anticancer, and environmental applications.

Mavzular

Nanoparticles: synthesis and applications Gold and Silver Nanoparticles Synthesis and Applications Laser-Ablation Synthesis of Nanoparticles

Identifikatorlar

DOI: 10.1002/slct.202501669

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