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Composition of Secondary Metabolites of Endophytic Fungus Aspergillus egypticus HT-166S isolated from Helianthus tuberósus

T.G. GulyamovaDepartment of Biochemistry and Biotechnology of Physiologically Active Compounds,B. S. OkhundedaevDepartment of Chemistry of Coumarins and Terpenoids, Institute of Chemistry of Plant Substances of the Academy of Sciences RU, UzbekistanХ. М. БобакуловDepartment of Physical Methods of Research, Institute of Chemistry of Plant Substances of the Academy of Sciences RU, UzbekistanS. Z. NishanbaevDepartment of Chemistry of Coumarins and Terpenoids, Institute of Chemistry of Plant Substances of the Academy of Sciences RU, UzbekistanI. D. Sham’yanovDepartment of Chemistry of Coumarins and Terpenoids, Institute of Chemistry of Plant Substances of the Academy of Sciences RU, UzbekistanD. M. RuzievaDepartment of Biochemistry and Biotechnology of Physiologically Active Compounds,L.I. AbdulmyanovaDepartment of Biochemistry and Biotechnology of Physiologically Active Compounds,Рано СаттароваDepartment of Biochemistry and Biotechnology of Physiologically Active Compounds,
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The component composition of the secondary metabolites Aspergillus egypticus HT-166S isolated from stem of Heliánthus tuberósus plant, which has the ability to strongly inhibit the activity of pancreatic α-amylase, was studied. Qualitative analysis of phytocompounds showed that among metabolites there were terpenoids, tannins, flavonoids, glycosides, saponins and alkaloids. The highest inhibitory activity was shown by ethyl acetate and benzene extracts of A. egypticus HT-166S. 42 components related to hydrocarbons and their functional derivatives, fatty acids, terpenoids, alkaloids, phenol carboxylic acids and their derivatives were identified by gas-liquid chromatography of benzene extraction.

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